Synthesis, structure, and biological activity of new metal carboxylate complexes containing a glycoluril fragment

Abstract

Cu(II), Ni(II), Zn(II), Co(II), Fe(II), Mn(II) carboxylates containing a pharmacophoric glycoluril fragment were obtained for the first time. The proposed structure of the complexes was established using elemental analysis, spectral methods, and magnetochemistry. Structure of one of the copper(II) complexes was proved by X-ray diffraction analysis. Antibacterial and fungicidal activity of all the compounds was studied. It was shown that the starting acids are inactive, while some complexes exhibit antibacterial activity.