Affiliation:
1. Ural Federal University
2. I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
3. South Ural State University
4. Ural State Medical University of the Ministry of Health of Russia
Abstract
Solvent-free reaction of 3,6-diaryl-1,2,4-triazine-5-carbonitriles with 2-amino-4-aryloxazoles was studied. In this case, the formation of 3- and 4-aryl-substituted pyridines (two isomeric products) in yields up to 20 and 27%, respectively, was found. This result is different from that for the reaction of 3-(2-pyridyl)-1,2,4-triazine-5-carbonitriles with these substrates. Thus, in this case, 2-amino-4-aryloxazoles act as synthetic analogues of arylacetylenes.
Publisher
The Russian Academy of Sciences