Blood physiology. erythrocyte based on the plenary lecture at the XXIV congress of the physiological society named after. I. P. Pavlova…-Reference-Cited by-同舟云学术

Blood physiology. erythrocyte based on the plenary lecture at the XXIV congress of the physiological society named after. I. P. Pavlova…

Published:2024-03-15 Issue:1 Volume:55 Page:
ISSN:0301-1798
Container-title:Успехи физиологических наук
language:
Short-container-title:Uspehi fiziologičeskih nauk

Author:

Ataullakhanov F. I.¹²³,Koleva L.¹²,Shakhidzhanov S. S.¹²

Affiliation:

1. Center for Theoretical Problems of Physical-Chemical Pharmacology, Russian Academy of Sciences

2. Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology Academy of Sciences

3. Moscow Institute of Physics and Technology

Abstract

Human red blood cells have a complex system for regulating cell volume and deformability. This is absolutely necessary to ensure good blood rheology both in large vessels and in the capillary network. The review examines the features of the erythrocyte structure that provide good gas transport functions and excellent blood rheology, despite the fact that erythrocytes occupy 40% of the blood volume. Providing these properties requires the participation of a number of metabolic systems, which allows the red blood cell to work effectively in the bloodstream for 100–120 days without the synthesis of new proteins.

Publisher

The Russian Academy of Sciences

Reference31 articles.

1. Атауллаханов Ф.И. Регуляция метаболизма в эритроцитах. Дис. ... докт. физ.-мат. наук. М.: НИИ по БИХС, 1982. 296 с.

2. Antonini E., Brunori M. Hemoglobin and myoglobin and their reactions with ligands // Frontiers in Biology. Amsterdam: North-Holland Pub. Co, 1971. V. 21. P. 436.

3. Ataullakhanov F.I., Korunova N.O., Spiridonov I.S. et. al. How erythrocyte volume is regulated, or what mathematical models can and cannot do for biology // Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 2009. V. 3. № 2. P. 101.

4. Ataullakhanov F.I., Martinov M.V., Shi Q., Vitvitsky V.M. Significance of two transmembrane ion gradients for human erythrocyte volume stabilization // PLoS ONE. 2022. V. 17. P. e0272675. https://doi.org/10.1371/journal.pone.0272675

5. Berg J.M., Tymoczko J.L., Gatto G.J. Jr., Stryer L. Hemoglobin: portrait of a protein in action // Biochemistry, 8th ed. New York: W.H. Freeman and Co, 2015. P. 191.