Affiliation:
1. Lomonosov Moscow State University
Abstract
The study investigated the effect of GABA in various concentrations and D-GB-115 at a concentration of 10–10 mol/ml on the behavior of Paramecium caudatum. It has been shown that GABA increases motor activity and changes the movement strategy of these protozoa, and the dose-effect relationship is domed, which can be explained by the presence of two types of GABA receptors in the outer membrane of paramecia: GABA-A and GABA-B. The range of active concentrations of GABA ranges from 10–6 to 10–16 mol/ml. The effect of pharmacological agents interacting with the GABA system on the behavior of infusoria: nembutal and D-GB-115.
Publisher
The Russian Academy of Sciences