Affiliation:
1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
2. Nguyen Tat Thanh University
3. Institute of Applied Materials Science, Vietnam Academy of Science and Technology
4. Mental Health Research Centre
Abstract
The effects of extracts of ten plant species growing in Russia and five species growing in Vietnam on the growth and survival of ciliates Tetrahymena pyriformis were studied. T. pyriformis is from the Protozoa subkingdom, which also includes pathogens of protozoan infections. Extraction of dried plants was carried out with acidic and alkaline aqueous solutions, as well as with an aqueous ethanol solution. Various amounts of extracts were added to the infusoria cells and the number of survived cells was recorded after 1 and 24 hours. We found that our samples of several plants, including wormwood, harmala, and licorice, similarly to those studied earlier, have antiprotozoal activity, which may indicate a sameness of secondary metabolites in plants from different regions. Using the ciliate T. pyriformis as a model organism, the presence of antiprotozoal activity in extracts of lilac, chondrilla, cinquefoil, hop and elm was shown for the first time.
Publisher
The Russian Academy of Sciences