Affiliation:
1. State Scientific Center of the Russian Federation – Federal Medical Biophysical Center named after A.I. Burnazyan, Federal Medical and Biological Agency of Russia
Abstract
The Fenton reaction was used to model a system in which particles similar to those formed during water radiolysis are created. A method of registering the chemiluminescence was applied to the analysis of the chlorophyllin-induced suppression of reactions caused by hydroxyl radicals. It has been shown that sodium copper chlorophyllin dose-dependently inhibits the chemiluminescence which accompanies the Fenton-mediated oxidation of phosphatidic acid. This leads us to conclude that copper chlorophyllin can inhibit the metabolism of lipid radiotoxins, also known as lipid peroxidation, caused by the attack of water radiolysis products to lipid molecules.
Publisher
The Russian Academy of Sciences