Affiliation:
1. Faculty of Biology, Lomonosov Moscow State University
Abstract
The extracellular proteinase – activator of human plasma prekallikrein was isolated from the culture fluid of the micromycete A. terreus 2, and their physicochemical, kinetic and biochemical properties were studied. It has been established that A. terreus 2 extracellular proteinase is a glycosylated serine proteinase with an isoelectric point of 4.6, molecular weight about 37 kDa and the optimum activity at pH 10.0 and a temperature of 37°C. In a number of properties, this proteinase is similar to proteinase – activator of protein C, which is produced by the micromycete A. ochraceus L-1.
Publisher
The Russian Academy of Sciences
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