LONG-TERM GENETIC AND EPIGENETIC DISORDERS IN PERSONS EXPOSED TO IONIZING RADIATION AND THEIR DESCENDANTS (review)

Author:

Kucher O., ,Vydyborets S.,

Abstract

The review is devoted to long-term genetic and epigenetic disorders in exposed individuals and their descendants, namely to cytogenetic effects in the Chornobyl NPP accident clean-up workers and their children, DNA methylation as an epigenetic modification of human genome. Data presented in review expand the understanding of risk of the prolonged exposure for the present and future generations, which is one of key problems posed by fundamental radiation genetics and human radiobiology. The Scientific Council meeting of NAMS approved the NRCRM Annual Report. Key words: Chornobyl NPP accident, cytogenetic effects, DNA methylation.

Publisher

National Research Center for Radiation Medicine of the NAMS of Ukraine

Subject

Radiology, Nuclear Medicine and imaging

Reference86 articles.

1. 1. Shevchenko VA, Snigiriova GP. [The importance of cytogenetic examination for assessing the consequences of the Chernobyl disaster]. Radiation Biology. Radioecology. 2006;46(2):133-139. Russian.

2. 2. Snigireva GP, Novitskaya NN, Popova GM. [The value of cytogenetic examination for predicting the long-term effects of radiation]. Radiation Biology. Radioecology. 2011;51(1):162-167. Russian.

3. 3. Vorobtsova IE, Semyonov AV. [Comprehensive cytogenetic characteristics of persons affected by the accident at the Chernobyl NPP]. Radiation Biology. Radioecology. 2006;46(2):140-152.

4. 4. Sevankaev AV, Mikhailova GF, Potetnya OI, Tsepenko VV, Khvostunov IK, Golub EV, et al. [Results of dynamic cytogenetic observation of children and adolescents living in radioactively contaminated areas after the Chernobyl accident]. Radiation Biology. Radioecology. 2005;45(1):5-15. Russian.

5. 5. Sevankaev AV, Parshin BC, Mikhailova GF, Khvostunov IK, Tsepenko VV, Potetnya OI, et al. [Comparative analysis of cytogenetic parameters with the morpho-functional state of thyroid in children and adolescents living from the moment of the accident at the Chernobyl NPP in the territories contaminated with radionuclides]. Radiation and Risk. 2006;15(1-2):134-145. Russian.

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