Of Mice, Not Men: When the Bench-to-Bedside Bridge Is Broken

Author:

Nikanjam Mina1,Kato Shumei1,Kurzrock Razelle23

Affiliation:

1. 1 Division of Hematology-Oncology, University of California San Diego, La Jolla, CA, USA

2. 2 Medical College of Wisconsin Cancer Center, Milwaukee, Wisconsin, USA

3. 3 Worldwide Network (WIN) for Personalized Cancer Therapy, Paris, France

Publisher

Innovative Healthcare Institute

Subject

Cancer Research,Oncology,Immunology,Immunology and Allergy

Reference11 articles.

1. Van Norman GA. Phase II trials in drug development and adaptive trial design. JACC Basic Transl Sci. 2019; 4: 428– 437.

2. Lewis MA. Return of results to patients: a gesture of respect and responsibility. J Immunother Precis Oncol. 2022; 5: 1.

3. Schuh JC. Trials, tribulations, and trends in tumor modeling in mice. Toxicol Pathol. 2004; 32(suppl 1): 53– 66.

4. Kaiser J. More than half of high-impact cancer lab studies could not be replicated in controversial analysis. Science. 2021; 374.

5. Pub. L. No. 110-85. Food and Drug Administration Amendments Act of 2007. 21 USC 301. Sep 27, 2007.

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Learning From Failure: Negative Trials in Oncology;Journal of Immunotherapy and Precision Oncology;2023-04-12

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