8-Aryloct-7-en-2,4,6-triones as Useful Precursors for the Regioselective Synthesis of Some New 2-Methyl-5-styryl-7-thioxo-6,7-dihydropyrazolo[1,5-c]pyrimidines

Abstract

Dehydroacetic acid, commonly abbreviated as DHA, and its derivatives have been extensively used as important intermediates in organic synthesis particularly for the synthesis of heterocyclic compounds. The reaction of 8-aryloct-7-en-2,4,6-triones (DHA-triones, readily prepared from commercially available DHA by the use of a multistep procedure) with thiosemicarbazide led the formation of some new 2-methyl-5-styryl-7-thioxo-6,7-dihydropyrazolo[1,5-c] pyrimidines.