HUBUNGAN ASUPAN PROTEIN DAN KADAR INTERLEUKIN-6 DENGAN KADAR HEMOGLOBIN PADA REMAJA PUTRI STATUS GIZI LEBIH

Abstract

ABSTRAKStatus gizi lebih dan anemia merupakan gangguan gizi yang sering muncul pada remaja putri. Remaja putri berisiko tinggi terjadi gangguan gizi tersebut karena cenderung mengalami peningkatan kebutuhan zat gizi, pembatasan pola konsumsi dan penyimpangan pola konsumsi. Asupan protein yang tinggi akan diubah menjadi lemak dan disimpan menjadi jaringan adiposa. Pada status gizi lebih, inflamasi kronik terjadi di jaringan lemak dan terjadi peningkatan sekresi sitokin proinflamasi, seperti interleukin 6 (IL-6). Kadar IL-6 yang tinggi meningkatkan kadar hepsidin, yang dapat menurunkan kadar besi (Fe) dalam sirkulasi. Penelitian ini  bertujuanmenganalisis hubungan antara asupan protein dan kadar IL-6 dengan kadar hemoglobin (Hb) pada remaja putri status gizi lebih.  Data asupan protein menggunakan metode food recall 24 jam dan SQ-FFQ (semi quantitativefood frequency questionare). Kadar IL-6 diukur dengan pemeriksaan ELISA. Kadar Hb diukur dengan metode cyanmethaemoglobin. Hasil penelitian ini menunjukkan bahwa asupan protein dan kadar IL-6 tidak berhubungan dengan kadar Hb (p=0,132) dan (p= 0,607). Penelitian selanjutnya diharapkan untuk menganalisis hubungan status gizi lebih pada remaja putri dengan kejadian anemia, seperti kadar hepsidin, globin dan feritin. Kata kunci: Asupan Protein, Kadar IL-6, Kadar Hb, Remaja Putri, Status Gizi Lebih ABSTRACTOvernutritional status and anemia are nutritional disorders that often occur in female adolescents. Female  adolescents are at high risk of nutritional disorders because they tend to experience an enhanchement nutritional needs, restrictions on consumption patterns and eating disorder. High protein intake will be converted into fat and stored into adipose tissue. In overnutrition adolescents, chronic inflammation occurs in fat tissue and also increasing proinflamation sitokin secretion, such as interleukin 6 (IL-6). High levels of IL-6 increases hepsidin levels, and decreases iron (Fe) level in circulation. This study aims to analyze the corelation of protein intake and IL-6 level with haemoglobin level in overnutrition female adolescents. Data of protein intake is taken through 24 hours food recall and SQ-FFQ (semi quantitative-food frequency questionare). IL-6 levels were measured by ELISA while Hb level is obtained thorugh cyanmethaemoglobin method. The results of this study there is no corelation between protein intake and IL-6 level toward Hb level (p=0,132) and (p= 0,607). It is suggested for other researcher to analyze corelation between overnutrition state in female adolescents and anemia symptomps such as hepsidin, globin, and feritin level.Keywords: Protein Intake, IL-6 Levels, Hemoglobin Levels, Adolescent Girls, Overnutritional Status