Comparison of secondary metabolite production in the sterigmatocystin and austinol cluster deletion strains in <i>Aspergillus nidulans</i>
Author:
Affiliation:
1. Department of Biological Science and Technology, Tokyo University of Science
Publisher
Japanese Association of Mycotoxicology
Subject
Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science
Link
https://www.jstage.jst.go.jp/article/myco/73/2/73_73-2-1/_pdf
Reference26 articles.
1. 1) Brown, D.W.; Yu, J.H.; Kelkar, H.S.; Fernandes, M.; Nesbitt, T.C.; Keller, N.P.; Adams, T.H.; Leonard, T.J. Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans. Proc. Natl. Acad. Sci. U. S. A. 1996, 93, 1418-1422.
2. 2) Yaegashi, J.; Oakley, B.R.; Wang, C.C.C. Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans. J. Ind. Micrbiol. Biotechnol. 2014, 41, 433-442.
3. 3) Lo, H.; Entwistle, R.; Guo, C.; Ahuja, M.; Szewczyk, E.; Hung, J.; Chiang, Y.; Oakley, B.R.; Wang, C.C.C. Two separate gene clusters encode the biosynthetic pathway for the meroterpenoids, austinol and dehydroaustinol in Aspergillus nidulans. J. Am. Chem. Soc. 2012, 134, 4709-4720.
4. 4) Yin, W.; Chooi, Y.H.; Smith, A.R.; Cacho, R.A.; Hu, Y.; White, T.C.; Tang, Y. Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans. ACS Synth. Biol. 2013, 2, 629-634.
5. 5) Nayak, T.; Szewczyk, E.; Oakley, C.E.; Osmani, A.; Ukil, L.; Murray, S.L.; Hynes, M.J.; Osmani, S.A.; Oakley B.R. A versatile and efficient gene-targeting system for Aspergillus nidulans. Genetics 2006, 172, 1557-1566.
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