Skin reaction due to intravenous bortezomib in a multiple myeloma patient

Abstract

Multiple myeloma (MM) is a hematological disease characterized by the increase of abnormal immunoglobulin. Clinical features of MM are anemia, recurrent bacterial infections, osteolytic bone lesions, and renal failure. Bortezomib is a frequently used agent in the treatment of disease. A male patient was admitted to our hematology department with dermal lesions. Physical findings revealed a gross hyperemic dermal area. The purpose of this case is to present the bortezomib associated rash and its treatment in a 71-year-old male patient treated with bortezomib. Although bortezomib is a frequently used agent in the treatment of MM, side effects may occur rarely. Therefore, during patient follow-up, drug side effects should be carefully evaluated.