Respiratory failure in children with oncohematological and immunological diseases: methods of treatment-Reference-Cited by-同舟云学术

Respiratory failure in children with oncohematological and immunological diseases: methods of treatment

Published:2020-03-28 Issue:1 Volume:19 Page:122-130
ISSN:2414-9314
Container-title:Pediatric Hematology/Oncology and Immunopathology
language:
Short-container-title:Voprosy gematologii/onkologii i immunopatologii v pediatrii

Author:

Ivanashkin A. Y.¹^ORCID,Lazarev V. V.²^ORCID

Affiliation:

1. Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation

2. Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation; N.I. Pirogov Russian National Research Medical University

Abstract

Acute respiratory distress syndrome (ARDS) against the background of a lung infection is one of the chief reasons for a fatal outcome in children with oncohematological and immunological diseases. This is due to the fact that in 16–24% of these patients, it is not possible to treat critical hypoxemia successfully using the traditional methods of mechanical ventilation (MV) of the lungs. For patients with ARDS, the method of choice for treating critical hypoxemia is extracorporeal membrane oxygenation (ECMO), but pronounced cytopenia, immunosuppression and hemostatic system disorders constitute absolute contraindications for ECMO, owing to a high risk of numerous fatal complications. Therefore, there remains currently a rather relevant problem: specifically, the search for alternative methods of mechanical ventilation, which would aim to improve oxygenation and gas exchange during severe forms of ARDS in children with oncohematological and immunological diseases. One of such methods is superimposed high-frequency jet ventilation (SHFJV).

Publisher

Fund Doctors, Innovations, Science for Children

Subject

Oncology,Hematology,Immunology,Immunology and Allergy,Pediatrics, Perinatology, and Child Health

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