Towards quantitative analysis of gene regulation by enhancers-Reference-Cited by-同舟云学术

Towards quantitative analysis of gene regulation by enhancers

Published:2017-09 Issue:9 Volume:9 Page:1219-1231
ISSN:1750-1911
Container-title:Epigenomics
language:en
Short-container-title:Epigenomics

Author:

Nizovtseva Ekaterina V¹,Todolli Stefjord²,Olson Wilma K²,Studitsky Vasily M¹³⁴

Affiliation:

1. Cancer Epigenetics Program, Fox Chase Cancer Center, 333 Cottman Ave., Philadelphia, PA 19422, USA

2. Department of Chemistry & Chemical Biology, Center for Quantitative Biology, Rutgers, the State University of New Jersey, 610 Taylor Rd., Piscataway, NJ 08854, USA

3. Biology Faculty, Moscow State University, Moscow 119991, Russia

4. Laboratory of Epigenetics, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia

Abstract

Enhancers are regulatory DNA sequences that can activate transcription over large distances. Recent studies have revealed the widespread role of distant activation in eukaryotic gene regulation and in the development of various human diseases, including cancer. Here we review recent progress in the field, focusing on new experimental and computational approaches that quantify the role of chromatin structure and dynamics during enhancer–promoter interactions in vitro and in vivo.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Genetics

Link

https://www.futuremedicine.com/doi/pdf/10.2217/epi-2017-0061

Reference134 articles.

1. Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

2. Short and long range activation by the SV40 enhancer

3. A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb

4. Chromatin domains, insulators, and the regulation of gene expression

5. Metazoan promoters: emerging characteristics and insights into transcriptional regulation

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