Pharmacogenomic considerations of xenograft mouse models of acute leukemia-Reference-Cited by-同舟云学术

Pharmacogenomic considerations of xenograft mouse models of acute leukemia

Published:2012-11 Issue:15 Volume:13 Page:1759-1772
ISSN:1462-2416
Container-title:Pharmacogenomics
language:en
Short-container-title:Pharmacogenomics

Author:

Guihard Soizic¹,Peyrouze Pauline¹,Cheok Meyling H²

Affiliation:

1. Jean-Pierre Aubert Research Center, INSERM U837, Institute for Cancer Research, 1 Place de Verdun, F-59045 Lille Cedex, France

2. Department of Hematology, University Hospital Center of Lille, CHU Lille, Boulevard du Professeur Leclercq, F-59037 Lille Cedex, France.

Abstract

The use of combination chemotherapy to cure acute lymphoblastic leukemia in children and acute myeloid leukemia in adults emerged for acute myeloid leukemia in the 1960s and for acute lymphoblastic leukemia in the 1980s as a paradigm for curing any disseminated cancer. This article summarizes recent developments and considerations in the use of acute leukemia xenografts established in immunodeficient mice to elucidate the genetic and genomic basis of acute leukemia pathogenesis and treatment response.

Publisher

Future Medicine Ltd

Subject

Pharmacology,Genetics,Molecular Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/pgs.12.158

Reference102 articles.

1. Development of functional human blood and immune systems in NOD/SCID/IL2 receptor γ chainnull mice

2. NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells

3. Comparison of human cord blood engraftment between immunocompromised mouse strains

4. Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rγnull mice generate a faster and more efficient disease compared to other NOD/scid-related strains

5. High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Co-Delivery of Daunorubicin and Homoharringtonine in Folic Acid Modified-Liposomes for Enhancing Therapeutic Effect on Acute Myeloid Leukemia;Journal of Pharmaceutical Sciences;2023-01

2. Murine Models of Acute Leukemia: Important Tools in Current Pediatric Leukemia Research;Frontiers in Oncology;2014-05-07

3. Animal Models in Pharmacogenomics;Handbook of Pharmacogenomics and Stratified Medicine;2014