In-stent restenosis of drug-eluting stents

Author:

Minha Sa’ar12,Pichard Augusto D12,Waksman Ron23

Affiliation:

1. Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA

2. MedStar Washington Hospital Center, 110 Irving Street, NW, Suite 4B-1, Washington, DC 20010, USA

3. Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA. .

Abstract

Drug-eluting stents (DES) have emerged as an improved alternative to bare-metal stents by demonstrating reduced rates of restenosis and target lesion revascularization. This emergence has led to the unrestricted use of DES for various indications and lesions, and subsequently revealed DES in-stent restenosis as a novel interventional therapeutic dilemma. Recent insights regarding the patho-physiological processes and therapeutic alternatives have added to the accumulated knowledge regarding the appropriate approach to this phenomenon. This review aims to detail the mechanism and clinical presentation of, and therapeutic strategies for, the treatment of DES in in-stent restenosis.

Publisher

Future Medicine Ltd

Subject

Cardiology and Cardiovascular Medicine,Molecular Medicine

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