Aging kidney: modern perspectives for an ‘old’ problem

Author:

Grosjean Fabrizio12,Vlassara Helen1,Striker Gary E1

Affiliation:

1. Division of Experimental Diabetes & Aging, Department of Geriatrics, Mount Sinai School of Medicine, New York, USA; Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, USA.

2. Section of Nephrology, Department of Internal Medicine, University of Pavia, Policlinico San Matteo, Pavia, Italy

Abstract

The scientific community and health systems will have to address the increasing incidence of reduced kidney function because of progressive global aging. The aim of this review is to describe the morphological and functional alterations that characterize the aging kidney and to suggest not only pharmaceutical pathways but also lifestyle changes that could be beneficially targeted.

Publisher

Future Medicine Ltd

Subject

Geriatrics and Gerontology,General Medicine

Reference153 articles.

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2. Prevalence of Chronic Kidney Disease in the United States

3. US Renal Data System. USRDS 2007 annual data report: atlas of chronic kidney disease and end-stage renal disease in the United States. NIH, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA (2007).

4. Chronic Kidney Disease and the Risks of Death, Cardiovascular Events, and Hospitalization

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