Value of galectin-3 in the diagnosis of acute coronary syndrome and the assessment of coronary artery lesions-Reference-Cited by-同舟云学术

Value of galectin-3 in the diagnosis of acute coronary syndrome and the assessment of coronary artery lesions

Published:2021-06 Issue:9 Volume:15 Page:647-657
ISSN:1752-0363
Container-title:Biomarkers in Medicine
language:en
Short-container-title:Biomarkers in Medicine

Author:

Li Xihong¹^ORCID,Qiu Qing¹,Tong Qingchao¹,Wang Yanzhong¹,Yu Haitao¹,Li Fengying¹,Xie Xinyou¹,Zhang Jun¹^ORCID

Affiliation:

1. Department of Clinical Laboratory, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

Abstract

Aim: To investigate the value of galectin-3 in the diagnosis of acute coronary syndrome (ACS) and the assessment of coronary artery lesions. Methodology: This study recruited 157 patients with coronary artery disease where 102 and 55 of them were subsequently grouped as ACS and non-ACS, respectively. The severity of coronary artery lesions was evaluated by Gensini score and the number of vessels involved. Results: Receiver operator characteristics analyses of galectin-3 yielded an area under the curve of 0.679 in diagnosing ACS. The galectin-3 levels were correlated with Gensini score and the number of vessels involved. Conclusion: Our study demonstrated that galectin-3 is an effective auxiliary biomarker for the diagnosis of ACS and assessment of coronary artery lesions.

Funder

Medical and Health Science and Technology Project of Zhejiang Province

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

Link

https://www.futuremedicine.com/doi/pdf/10.2217/bmm-2020-0610

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