1. Internal Medicine, Department of Medicine, Università degli Studi di Perugia, 1 piazzale Gambuli, 06129 Perugia, Italy
2. First Clinic of internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy
3. IRCCS Ospedale Policlinico San Martino, Genoa, Italian Cardiovascular Network, 10 Largo Benzi, 16132 Genoa, Italy