De Ritis ratio: how effectively can we use in bladder cancer management?-Reference-Cited by-同舟云学术

De Ritis ratio: how effectively can we use in bladder cancer management?

Published:2020-10 Issue:15 Volume:14 Page:1453-1460
ISSN:1752-0363
Container-title:Biomarkers in Medicine
language:en
Short-container-title:Biomarkers in Medicine

Author:

Yilmaz Mehmet¹^ORCID,Sahin Yusuf¹,Ates Huseyin A²,Hacibey Ibrahim¹,Cil Gokhan¹

Affiliation:

1. Department of Urology, University of Health Sciences, Bagcilar Training & Research Hospital, Istanbul, Turkey

2. Department of Urology, Gebze Fatih State Hospital, Kocaeli, Turkey

Abstract

Background: This study aims to determine the relationship between the pre-operative De Ritis ratio (DRR) and bladder cancer (BCa) pathological subtypes. Results & methodology: A total of 248 patients with primary BCa were included. Univariate and multivariate analyses were performed to identify whether DRR can be a risk factor for the presence of carcinoma in situ (C IS). There was a statistically significant difference between the nonmuscle invasive BCa risk groups and the muscle-invasive BCa group according to the median DRR levels (p < 0.001). DRR was an independent risk factor for the presence of C IS in multivariate analysis (OR: 1.909; 95% CI: 0.030–0.196; p = 0.008). Discussion & conclusion: DRR can be considered as an independent risk factor for the presence of C IS in patients with primary BCa.

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

Link

https://www.futuremedicine.com/doi/pdf/10.2217/bmm-2020-0212

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