Circular RNA as a potential diagnostic and/or therapeutic target for endometriosis-Reference-Cited by-同舟云学术

Circular RNA as a potential diagnostic and/or therapeutic target for endometriosis

Published:2020-09 Issue:13 Volume:14 Page:1277-1287
ISSN:1752-0363
Container-title:Biomarkers in Medicine
language:en
Short-container-title:Biomarkers in Medicine

Author:

Dana Parisa M¹,Taghavipour Mona²,Mirzaei Hamed¹,Yousefi Bahman³⁴,Moazzami Bahram⁵,Chaichian Shahla⁵,Asemi Zatollah¹

Affiliation:

1. Research Center for Biochemistry & Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, IR Iran

2. Department of Gynecology & Obstetrics, Ramsar Campus, Mazandaran University of Medical Sciences, Sari, Iran

3. Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

4. Department of Biochemistry, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

5. Pars Advanced & Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran

Abstract

Endometriosis is a pathology form of endometrium that behaves in a similar way to malignancies, such as invasion and resistance to apoptosis. Circular RNAs (CircRNAs) are a class of noncoding RNAs that have several biological functions including, miRNA sponging, sequestering of proteins, enhancing parental gene expression and translation resulting in polypeptides. In this review, we highlighted the roles of circRNAs as potential diagnostic and therapeutic biomarkers in endometriosis. Moreover, we summarized the roles of circRNAs in the pathogenesis of endometriosis via different signaling pathways, such as the miRNA network and apoptosis.

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

Link

https://www.futuremedicine.com/doi/pdf/10.2217/bmm-2020-0167

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