In Mexican Mestizos the HCP5 rs2395029 SNP may be a genetic marker for screening abacavir hypersensitivity
Author:
Affiliation:
1. Laboratorio Medico Polanco, Insurgentes Sur 1228 3rd Floor, Col. Del Valle, México DF 03100, México
2. Instituto Nacional de Medicina Genómica, 4809 Periférico Sur, Col Arenal Tepepan, México DF 14610, México.
Abstract
Publisher
Future Medicine Ltd
Subject
Pharmacology,Genetics,Molecular Medicine
Link
https://www.futuremedicine.com/doi/pdf/10.2217/pgs.11.169
Reference5 articles.
1. Tag SNPs of the ancestral haplotype 57.1 do not substitute HLA-B*57:01 typing for eligibility to abacavir treatment in the Italian population
2. Association of the genetic marker for abacavir hypersensitivity HLA-B*5701 with HCP5 rs2395029 in Mexican Mestizos
3. NolanD, Thorborn D, Schaefer Met al.Genetic factors predicting abacavir hypersensitivity and tolerance inHLA-B*5701positive individuals: combined analysis from PREDICT-1, SHAPE and a multinational study. Presented at:15th Conference on Retroviruses and Opportunistic Infections. Boston, MA, USA, 3–6 February 2008.
4. TheHCP5Single‐Nucleotide Polymorphism: A Simple Screening Tool for Prediction of Hypersensitivity Reaction to Abacavir
5. Use of the HCP5 single nucleotide polymorphism to predict hypersensitivity reactions to abacavir: correlation with HLA-B*5701
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1. Pharmacogenetic effects of single nucleotide polymorphisms commonly associated with antiretroviral therapy metabolism;HIV Infection and Immunosuppressive Disorders;2022-11-10
2. Validation of two commercial real-time PCR assays for rapid screening of the HLA-B*57:01 allele in the HIV clinical laboratory;Journal of Virological Methods;2016-11
3. The frequency of HLA-B∗57:01 and the risk of abacavir hypersensitivity reactions in the majority population of Costa Rica;Human Immunology;2014-11
4. Development of multiplex pyrosequencing for HLA-B*57:01 screening using single nucleotide polymorphism haplotype;Journal of Clinical Pharmacy and Therapeutics;2014-05-26
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