Pharmacogenomics of cytarabine in childhood leukemia
Author:
Affiliation:
1. Department of Experimental & Clinical Pharmacology, College of Pharmacy, PUMA-Institute of Personalized Medicine, Institute of Human Genetics, 14-281 Moos Tower, Delaware Street SE, MN, USA.
Publisher
Future Medicine Ltd
Subject
Pharmacology,Genetics,Molecular Medicine
Link
https://www.futuremedicine.com/doi/pdf/10.2217/pgs.11.148
Reference22 articles.
1. Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with acute leukemia.
2. Correlation of cytotoxicity with incorporation of ara-C into DNA.
3. Lethality of human myeloblasts correlates with the incorporation of arabinofuranosylcytosine into DNA.
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2. Evaluation of the impact of single-nucleotide polymorphisms on treatment response, survival and toxicity with cytarabine and anthracyclines in patients with acute myeloid leukaemia: a systematic review protocol;Systematic Reviews;2019-05-03
3. Comprehensive Ara-C SNP score predicts leukemic cell intracellular ara-CTP levels in pediatric acute myeloid leukemia patients;Pharmacogenomics;2018-09-01
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