The role of implantable devices to treat atrial fibrillation

Abstract

In the last decades several nonpharmacological therapies for the treatment and prevention of atrial fibrillation (AF) have been developed. Pacemakers play a potential important role in the nonpharmacological management of AF. In patients with sinus node dysfunction both, atrial and dual-chamber pacing, have been proven to prevent or delay progression to permanent AF compared with ventricular pacing alone. However, in patients without conventional indications for pacing, the utility of pacemakers as a stand-alone therapy has not yet proven. Following the positive results obtained by low energy internal defibrillation, specific implantable devices for AF cardioversion have been developed. Despite implantable atrial defibrillators being possible alternatives for drug refractory AF, industry did not further develop these due to shock discomfort. Newer implantable pulse generators also offer data storage that permits detection of asymptomatic AF. Such a help provided by implantable devices, has been enhanced by the development and spread out of remote monitoring systems.