Sphingolipid regulators of cellular dysfunction in Type 2 diabetes mellitus: a systems overview
Author:
Affiliation:
1. Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA
2. Ralph H Johnson Veterans Affairs Medical Center, Charleston, SC 29401, USA
Publisher
Informa UK Limited
Subject
Cardiology and Cardiovascular Medicine,Endocrinology, Diabetes and Metabolism
Link
https://www.tandfonline.com/doi/pdf/10.2217/clp.14.37
Reference194 articles.
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2. Modan M, Halkin H, Almag S et al. Hyperinsulnemia: a link between hypertension, obesity, and glucose intolerance. J. Clin. Invest. 75, 809–817 (1985).
3. Summers SA. Ceramides in insulin resistance and lipotoxicity. Prog. Lipid. Res. 45, 42–72 (2006).
4. Straczkowski M, Kowalska I, Baranowski M et al. Increased skeletal muscle ceramide level in men at risk of developing Type 2 diabetes. Diabetologia 50, 2366–2373 (2007).
5. Hu W, Bielawski J, Samad F, Merrill AH Jr, Cowart LA. Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity. J. Lipid. Res. 50, 1852–1862 (2009).
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