Links between Alcohol Consumption and Breast Cancer: A Look at the Evidence

Author:

Liu Ying1,Nguyen Nhi1,Colditz Graham A12

Affiliation:

1. Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA

2. Alvin J Siteman Cancer Center at Barnes-Jewish Hospital & Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA

Abstract

Alcohol consumption by adult women is consistently associated with risk of breast cancer. Several questions regarding alcohol and breast cancer need to be addressed. Menarche to first pregnancy represents a window of time when breast tissue is particularly susceptible to carcinogens. Youth alcohol consumption is common in the USA, largely in the form of binge drinking and heavy drinking. Whether alcohol intake acts early in the process of breast tumorigenesis is unclear. This review aims to focus on the influences of timing and patterns of alcohol consumption and the effect of alcohol on intermediate risk markers. We also review possible mechanisms underlying the alcohol-breast cancer association.

Publisher

SAGE Publications

Subject

General Medicine

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