The influences of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of simvastatin, in relation to CYP3A4 inhibition
Author:
Affiliation:
1. Clinical Research Division, National Institute of Food & Drug Safety Evaluation, Ministry of Food & Drug Safety, Cheongju, Republic of Korea
2. School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea
Abstract
Publisher
Future Medicine Ltd
Subject
Pharmacology,Genetics,Molecular Medicine
Link
https://www.futuremedicine.com/doi/pdf/10.2217/pgs-2016-0199
Reference38 articles.
1. Statin-Induced Rhabdomyolysis: A Comprehensive Review of Case Reports
2. The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update
3. Clinical Pharmacokinetics and Practical Applications of Simvastatin
4. Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells
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