The dynamics of the hand, foot and mouth disease epidemic from 2008 to 2016 in Zhenjiang city, China-Reference-Cited by-同舟云学术

The dynamics of the hand, foot and mouth disease epidemic from 2008 to 2016 in Zhenjiang city, China

Published:2018-07 Issue:9 Volume:13 Page:1029-1040
ISSN:1746-0913
Container-title:Future Microbiology
language:en
Short-container-title:Future Microbiology

Author:

Mao Lingxiang¹,Fu Xuemin²,Wu Jing³,Shen Li⁴,Gu Jiaqi³,Yuan Zhaohu⁴,Chen Jianguo¹,Zou Xinran³,Zhang Chiyu²

Affiliation:

1. Department of Clinical Laboratory, Affiliated People's Hospital, Jiangsu University, Zhenjiang, PR China

2. Pathogen Discovery & Big Data Center, CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai 200031, PR China

3. School of Medical Science & Laboratory Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu, PR China

4. Zhenjiang Center of Disease Control & Prevention, 9 Huangshan South Road, Zhenjiang, Jiangsu, PR China

Abstract

Aim: To investigate the hand, foot and mouth disease (HFMD) epidemic in Zhenjiang, China from 2008 to 2016. Materials & methods: A total of 37,202 HFMD cases were investigated and 3707 nasopharyngeal swabs were detected for enterovirus RNA using RT-quantitative PCR. Results: We first reported a mixed pattern of HFMD seasonal epidemic with a combination of single-peak and two-peak patterns in alternate years, and the occurrence of sporadic and epidemic outbreaks of HFMD in kindergartens in Zhenjiang. Children younger than 4 years of age were highly vulnerable to HFMD, and home children and boys had higher risk to develop severe HFMD than nursery children and girls, respectively. Among tested samples, 1709 (46.1%) were detected as enterovirus RNA positive. Conclusion: This study first presents the dynamic of the HFMD epidemic in Zhenjiang from 2008 to 2016.

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fmb-2018-0063

Reference34 articles.

1. Virology, epidemiology, pathogenesis, and control of enterovirus 71

2. Clinical features, diagnosis, and management of enterovirus 71

3. Murphy FA, Fauquet CM, Bishop DH Virus Taxonomy: Classification And Nomenclature Of Viruses. Springer Science & Business Media, Berlin Heidelberg, Germany, 10 (2012).

4. Survey of enterovirus infections from hand, foot and mouth disease outbreak in china, 2009

5. An outbreak of coxsackievirus A6 hand, foot, and mouth disease associated with onychomadesis in Taiwan, 2010

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