Advances in sampling and screening for chlamydia

Author:

Hocking Jane S1,Guy Rebecca2,Walker Jennifer3,Tabrizi Sepehr N4

Affiliation:

1. Centre for Women’s Health, Gender & Society, University of Melbourne, Victoria, Australia

2. Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia

3. Centre for Excellence in Rural Sexual Health, Rural Health Academic Centre, University of Melbourne, Victoria, Australia

4. Department of Molecular Microbiology, Royal Women’s Hospital; Department of Obstetrics & Gynecology, University of Melbourne & Murdoch Children’s Research Institute, Victoria, Australia.

Abstract

Chlamydia is the most commonly diagnosed bacterial sexually transmitted infection in the developed world, with diagnosis rates continuing to increase each year. As chlamydia is largely asymptomatic, screening and treatment is the main way to detect cases and reduce transmission. Recent advances in self-collected specimens and laboratory tests has made chlamydia screening easier to implement as well as possible in nonclinical settings. This review will discuss new approaches to specimen collection and how these have expanded opportunities for reaching target populations for chlamydia screening. Furthermore, it will discuss how advanced molecular microbiological methods can be used with self-collected specimens to further our knowledge of the epidemiology of chlamydia and the dynamics of transmission.

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

Reference221 articles.

1. SchachterJ, Stephens RS. Biology ofChlamydia trachomatis. In:Sexually Transmitted Disease (4th Edition). Holmes KK, Sparling PF, Stamm WEet al.(Eds). McGraw-Hill, NY, USA,555–574 (2008).

2. WHO.Global Incidence and Prevalence of Selected Curable Sexually Transmitted Infections. WHO, Switzerland (2012).

3. Current crisis or artifact of surveillance: insights into rebound chlamydia rates from dynamic modelling

4. Trends in Chlamydia Positivity Over Time Among Women in Melbourne Australia, 2003 to 2007

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