Immune-related gigantomastia: a case study

Author:

Lozito Alessia1,Gemelli Maria2ORCID,Micello Donata3,Vinci Valeriano14,Pelosi Giuseppe35,Ricotta Riccardo2

Affiliation:

1. Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, 20090, Italy

2. Medical Oncology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) MultiMedica, Milan, 20099, Italy

3. Inter-Hospital Division of Pathology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) MultiMedica, Milan, Italy

4. Humanitas Clinical & Research Center, IRCCS, Rozzano, Milan, 20089, Italy

5. Department of Oncology & Hemato-Oncology, University of Milan, Milan, Italy

Abstract

PD-1/PDL-1 inhibitors have revolutionized cancer treatment, especially in lung cancer. Despite their efficacy, a new spectrum of side effects, called immune-related adverse events, may occur and their management could be difficult. Gigantomastia, a rare condition characterized by excessive growth of the breasts, has been associated with some drugs, but no correlation with immunotherapy has ever been reported. Here, we report the case of a possible immune-related gigantomastia.

Publisher

Future Medicine Ltd

Subject

Oncology,Immunology,Immunology and Allergy

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1. Nivolumab;Reactions Weekly;2023-10-14

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