Responsible innovation in stem cell research: using responsibility as a strategy

Author:

Assen LS1ORCID,Jongsma KR1ORCID,Isasi R2ORCID,Utomo L3ORCID,Tryfonidou MA3ORCID,Bredenoord AL4ORCID

Affiliation:

1. Department of Medical Humanities, Julius Center for Health Sciences & Primary Care, University Medical Center Utrecht, Utrecht, GA, 3508, The Netherlands

2. Department of Human Genetics & Interdisciplinary Stem Cell Institute, Dr. John T. Macdonald Foundation, University of Miami Miller School of Medicine, Miami, FL 33136, USA

3. Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, CM, 3584, The Netherlands

4. Erasmus School of Philosophy, Erasmus University Rotterdam, Rotterdam, DR, 3000, The Netherlands

Abstract

Responsible innovation has been introduced as an important condition for advancing the field of regenerative medicine. This is reflected in the frequent references to responsible research conduct and responsible innovation in guidelines and recommendations in academic literature. The meaning of responsibility, how responsibility could be fostered and the context in which responsibilities should be enacted, however, remain unclear. The goal of this paper is to clarify the concept of responsibility in stem cell research and to illustrate how this concept could inform strategies to deal effectively with the ethical implications of stem cell research. Responsibility can be dissected into four categories: responsibility-as-accountability, responsibility-as-liability, responsibility-as-an-obligation and responsibility-as-a-virtue. The authors focus on responsible research conduct and responsible innovation in general to move beyond the scope of research integrity and illustrate that different notions of responsibility have different implications for how stem cell research is organized.

Funder

H2020 European Research Council

Publisher

Future Medicine Ltd

Subject

Embryology,Biomedical Engineering

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