Research progress in seed cells for cartilage tissue engineering

Author:

Bai Baoshuai123,Hou Mengjie23,Hao Junxiang123,Liu Yanhan4,Ji Guangyu5ORCID,Zhou Guangdong123ORCID

Affiliation:

1. Research Institute of Plastic Surgery, Wei Fang Medical University, Wei Fang, Shandong, 261053, China

2. Shanghai Key Laboratory of Tissue Engineering, Department of Plastic & Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200240, China

3. National Tissue Engineering Center of China, Shanghai, 200240, China

4. Shanghai JiaoTong University School of Medicine, Shanghai, 200240, China

5. Department of Thoracic Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200240, China

Abstract

Cartilage defects trouble millions of patients worldwide and their repair via conventional treatment is difficult. Excitingly, tissue engineering technology provides a promising strategy for efficient cartilage regeneration with structural regeneration and functional reconstruction. Seed cells, as biological prerequisites for cartilage regeneration, determine the quality of regenerated cartilage. The proliferation, differentiation and chondrogenesis of seed cells are greatly affected by their type, origin and generation. Thus, a systematic description of the characteristics of seed cells is necessary. This article reviews in detail the cellular characteristics, research progress, clinical translation challenges and future research directions of seed cells while providing guidelines for selecting appropriate seed cells for cartilage regeneration.

Funder

The Program of Shanghai Academic/Technology Research Leader

The Shanghai Collaborative Innovation Program on Regenerative Medicine and Stem Cell Research

The Clinical Research Plan of SHDC

The National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Future Medicine Ltd

Subject

Embryology,Biomedical Engineering

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3