Clinical & diagnostic issues in catatonia

Abstract

The concept of catatonia was formulated in the 1860s by Karl Ludwig Kahlbaum. He coined and gave the name catatonia to the syndromic entity in which the mood symptoms (depression and mania) were primary, and motor symptoms (mutism, negativism, stereotypies, catalepsy and verbigeration) the most characteristic. Although the name has remained stable, this concept has changed in the last century concerning the details of its definition until the current integrative approach in DSM 5. Catatonic phenomena are main components of the ‘motor abnormalities’ domain in psychiatric, neurologic and general medical disorders and they have to be evaluated in the context of a full psychopatological and neurological examination. In this article, we make a review about clinical and diagnostic issues in catatonia. Catatonic phenomena comprise both state and trait characteristics and have prognostic validity in psychosis. Moreover, providing that motor abnormalities are closer to neurobiological underpinnings than other psychotic symptoms (e.g., positive symptoms of schizophrenia), catatonic phenomena should be studied specifically as targets for neurobiological research.