A promising road with challenges: where are gold nanoparticles in translational research?-Reference-Cited by-同舟云学术

A promising road with challenges: where are gold nanoparticles in translational research?

Published:2014-10 Issue:15 Volume:9 Page:2353-2370
ISSN:1743-5889
Container-title:Nanomedicine
language:en
Short-container-title:Nanomedicine

Author:

Bao Chenchen¹,Conde João²,Polo Ester³,del Pino Pablo⁴,Moros Maria⁵,Baptista Pedro V⁶,Grazu Valeria⁵,Cui Daxiang¹,de la Fuente Jesus M¹⁵⁷

Affiliation:

1. Department of Instrument Science & Engineering, School of Electronic Information & Electrical Engineering, Research Institute of Translation Medicine, Shanghai Jiao Tong University, Dongchuan Road 800, 200240 Shanghai, People's Republic of China

2. Massachusetts Institute of Technology, Institute for Medical Engineering & Science, Harvard–MIT Division for Health Sciences & Technology, E25-449 Cambridge, MA, USA

3. Center for BionanoInteractions (CBNI), University College Dublin, Belfield, 4 Dublin, Ireland

4. CIC BiomaGUNE, Paseo Miramon 182, 20009, San Sebastian, Spain

5. Instituto de Nanociencia de Aragon-Universidad de Zaragoza, Edif I+D, C/ Mariano Esquillor s/n, Zaragoza, 50018, Spain

6. CIGMH, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, 2829-516 Caparica, Portugal

7. Instituto de Ciencia de Materiales de Aragón-CSIC/Universidad de Zaragoza, C/Pedro Cerbuna 12, Zaragoza, 50009, Spain

Abstract

Nanoenabled technology holds great potential for health issues and biological research. Among the numerous inorganic nanoparticles that are available today, gold nanoparticles are fully developed as therapeutic and diagnostic agents both in vitro and in vivo due to their physicochemical properties. Owing to this, substantial work has been conducted in terms of developing biosensors for noninvasive and targeted tumor diagnosis and treatment. Some studies have even expanded into clinical trials. This article focuses on the fundamentals and synthesis of gold nanoparticles, as well as the latest, most promising applications in cancer research, such as molecular diagnostics, immunosensors, surface-enhanced Raman spectroscopy and bioimaging. Challenges to their further translational development are also discussed.

Publisher

Future Medicine Ltd

Subject

Development,General Materials Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering

Link

https://www.futuremedicine.com/doi/pdf/10.2217/nnm.14.155

Reference121 articles.

1. Gold nanoparticle research before and after the Brust–Schiffrin method

2. Synthesis of thiol-derivatised gold nanoparticles in a two-phase Liquid–Liquid system

3. Tailoring Surface Plasmons through the Morphology and Assembly of Metal Nanoparticles

4. Plasmonic energy transfer in periodically doped graphene

Cited by 58 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Performance enhancement of the lateral flow immunoassay by use of composite nanoparticles as signal labels;TrAC Trends in Analytical Chemistry;2024-01

2. Gold nanoparticles for delivery of nucleic acid constructs for cancer treatment;Gold Nanoparticles for Drug Delivery;2024

3. Nano-dimensional gold synthesis for biomedical applications: upscaling and challenges;Particulate Science and Technology;2023-05-18

4. Metallic nanoscale-knife application in cancer theranostics;Smart Materials in Medicine;2023

5. Colloidal Synthesis of Metal Nanocrystals: From Asymmetrical Growth to Symmetry Breaking;Chemical Reviews;2022-12-22