Activity of chemokines in prostate and renal tumors and their potential role as future therapeutic targets-Reference-Cited by-同舟云学术

Activity of chemokines in prostate and renal tumors and their potential role as future therapeutic targets

Published:2017-05 Issue:12 Volume:13 Page:1105-1114
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Cimadamore Alessia¹,Scarpelli Marina¹,Piva Francesco²,Massari Francesco³,Gasparrini Silvia¹,Doria Andrea¹,Cheng Liang⁴,Lopez-Beltran Antonio⁵⁶,Montironi Rodolfo¹

Affiliation:

1. Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy

2. Department of Specialist Clinical & Odontostomatological Sciences, Università Politecnica delle Marche, Ancona, Italy

3. Division of Oncology, S Orsola-Malpighi Hospital, Bologna, Italy

4. Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA

5. Department of Surgery & Pathology, Faculty of Medicine, Cordoba University Medical School, Cordoba, Spain

6. Champalimaud Clinical Center, Lisbon, Portugal

Abstract

Chemokines are a class of low-molecular-weight proteins that induce chemotaxis and are implicated in the modulation of angiogenesis. The imbalance among angiogenic and antiangiogenic chemokines can promote the development of several conditions, including chronic inflammation, dysplastic transformation and cancer. In this review, we describe the activity and clinical significance of chemokines in prostate and renal tumors and provide an update on ongoing studies in this setting.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fon-2016-0481

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