Survey of current practices from the International Stereotactic Body Radiotherapy Consortium (ISBRTC) for head and neck cancers

Author:

Karam Irene1,Yao Min2,Heron Dwight E3,Poon Ian1,Koyfman Shlomo A4,Yom Sue S5,Siddiqui Farzan6,Lartigau Eric7,Cengiz Mustafa8,Yamazaki Hideya9,Hara Wendy10,Phan Jack11,Vargo John A3,Lee Victor12,Foote Robert L13,Harter K William14,Lee Nancy Y15,Sahgal Arjun1,Lo Simon S16

Affiliation:

1. Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Science Center, University of Toronto, Toronto, ON, Canada

2. Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, OH, USA

3. Department of Radiation Oncology, Otolaryngology, Head & Neck Surgery, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA

4. Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA

5. Department of Radiation Oncology, University of California, San Francisco, CA, USA

6. Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA

7. Department of Radiation Oncology, Centre Oscar Lambret, Lille, France

8. Department of Radiation Oncology, Hacettepe University, Ankara, Turkey

9. Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan

10. Department of Radiation Oncology, Stanford University, Stanford, CA, USA

11. Department of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA

12. Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China

13. Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA

14. Department of Radiation Oncology, Georgetown University & Vincent T Lombardi Comprehensive Cancer Center, Washington, DC, USA

15. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA

16. Department of Radiation Oncology, University of Washington School of Medicine, Seattle, WA, USA

Abstract

Aim: To provide a multi-institutional description of current practices of stereotactic body radiotherapy (SBRT) for head and neck cancer. Materials & methods: 15 international institutions with significant experience in head and neck SBRT were asked to complete a questionnaire covering clinical and technical factors. Results: SBRT is used 10–100% of the time for recurrent primary head and neck cancer, and 0–10% of the time in newly diagnosed disease. Five centers use a constraint for primary disease of 3–5 cm and 25–30 cc. Nine institutions apply a clinical target volume expansion of 1–10 mm and 14 use a planning target volume margin of 1–5 mm. Fractionation regimens vary between 15 and 22 Gy in 1 fraction to 30–50 Gy in 5 or 6 fractions. The risk of carotid blowout quoted in the re-irradiation setting ranges from 3 to 20%. Conclusion: There is considerable heterogeneity in patient selection and techniques in head and neck SBRT practice among experienced centers.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

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