Back to the future: the ribosome as an antibiotic target
Author:
Affiliation:
1. Rib-X Pharmaceuticals, Inc., 300 George Street, Suite 301, New Haven CT 0651, USA.
Publisher
Future Medicine Ltd
Subject
Microbiology (medical),Microbiology
Link
https://www.futuremedicine.com/doi/pdf/10.2217/17460913.2.6.571
Reference26 articles.
1. NIAID. The problem of antibiotic resistance, NIAID fact sheet. April 2006.NIAID(2006).
2. Invasive Methicillin-Resistant Staphylococcus aureus Infections in the United States
3. MaaloeO: Regulation of the protein synthesis machinery. In:Biological Regulation and Development. Goldberg RF (Ed.). Vol. 1. Plenum Publishing Corp., NY, USA487–542 (1979).
4. The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
5. High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium
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1. Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA;Proceedings of the National Academy of Sciences;2014-04-09
2. Mitochondrial translational inhibitors in the pharmacopeia;Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms;2012-09
3. Influence of mtDNA genetic variation on antibiotic therapy;Pharmacogenomics;2010-09
4. Antibiotics Targeting the Ribosome: Structure-Based Design and the Nobel Prize;Annual Reports in Computational Chemistry;2010
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