The management of patients with cancer of unknown primary in middle-income countries: an ESO-AROME survey
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Published:2021-01
Issue:2
Volume:17
Page:151-157
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ISSN:1479-6694
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Container-title:Future Oncology
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language:en
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Short-container-title:Future Oncology
Author:
Pavlidis Nicholas12ORCID, Todorovic Vladimir3, Rassy Elie45, Khaled Hussein6, Peccatori Fedro78, Eniu Alex29, Aapro Matti810, Gligorov Joseph11, Vrbanec Damir, Kattan Joseph, Daaboul Hamid Elia, Dbouk Haifaa, Abdayem Pamela, Bassil Josiane, Al Ghor Maya, Milasevic Nikola, Kuten Abraham, Farhat Fadi, Haddad Fadi, Rawadi Elsa, Djordjevic Fedja, Luzi Manjola, Mano Anastela, Kapisazovic Elma, Dzunic Miljana, Simonovska Marija, Popovic Jelena, Krstić Miloš, Bojovska Trajanovska Valentina, Tula Jonida, Konsoulova Assia, Qordja Manjola, Iuliana Pantelimon, Vertakova Krakovska Bibiana, Tola Elona, Sehic-Kozica Erns, Borilova Simona, Ademi Sabo, Andrei Popescu, Dimitrijevic Jelena, Matei Ramona, Ziolkowska Barbara, Milka Vještica, Subasic-Tankovic Selma, Vasic Ljiljana, Omut Cristiana Bianca, Ruci Erald, Zist Andrje, Ceriman Krstic Vesna, Sulejmanovic Samra, Saber Abdelhalim Mohyeldin, El Mahfoudi Amal, Xenophontos Eleni, Abdelbakey Fatma, Isik Arda, Ezzi Mohammed, Khelifi Touhami Soufiane, Zawam Hussam, Shouman Mohamed, Sayed Elkhodary Hoda, Abdel aziz Riham, Hadeya Osman Mousa Ahmed, Khalil Khaled, Hijri Fatima Zahra, Qawasmeh Jalal, Fikry Caroline, Mohammed Afif, Jidveian Popescu Mara, Salah Ebtehal, Ezzeldin Mohamed, Ait Erraisse Mohamed, Mosoiu Silvia, Mohsen Khalil Mariam, Mahmoud Hegazy Hanady, Awad Omar, Atef Elnemr Hanan, Mester Andra, Qeraj Kleva, Vidovic Vladimir, Karaulli Erald, Mohsen Khalil Mariam, Iljovska Marina, Vanessa Moldoveanu, Berić Jozić Gordana, Shaheen Haitham, Djundeva Jasmina, Ismail Mohamed, Youstina Youstina
Affiliation:
1. University of Ioannina, Niacrhos Avenue, Ioannina, 45 000, Greece 2. European School of Oncology College, 20121, Milan, Italy 3. Oncology & Radiotherapy Clinic, Clinical Center of Montenegro, University of Montenegro, 81000, Podgorica, Montenegro 4. Department of Medical Oncology, Institut Gustave Roussy, 94800, Villejuif, France 5. Faculty of Medicine, Department of Oncology, Saint Joseph University, 11-5076, Beirut, Lebanon 6. Medical Oncology Department, National Cancer Institute, Cairo University, 11796, Giza, Egypt 7. Fertility & Procreation Unit, Gynecologic Oncology Program, European Institute of Oncology IRCCS, 20141, Milan, Italy 8. European School of Oncology, 20121, Milan, Italy 9. Hospital Riviera Chablais, 1847, Rennaz, Switzerland 10. Breast Center, Genolier Cancer Centre, 1272, Genolier, Switzerland 11. Institut Universitaire de Cancerologie APHP-Sorbonne Université, 75006, Paris, France
Abstract
Aim: To report on the management strategies in patients with cancer of unknown primary (CUP) in middle-income countries. Methods: We conceived a survey of 20 items concerning the management of patients with CUP in daily clinical practice. Only participants from lower- and higher-middle-income countries, as per the World Bank Classification, were eligible for this study. Results: The indications for the first-line treatment did not differ between the two economic regions, whereas those for second-line treatment were more prevalent in higher-middle-income countries. The use of targeted therapy based on immunohistochemistry alone was higher in lower-middle-income countries, although the access to CUP classifiers was similar between the two regions. Conclusions: Proper recommendations must ensure that the economic burden is minimized and that other benefits outweigh the limited survival benefit achieved in patients with CUP.
Publisher
Future Medicine Ltd
Subject
Cancer Research,Oncology,General Medicine
Cited by
2 articles.
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