Symptoms and their implications on quality of life and psychological distress in sarcoma patients

Author:

Maggi Gabriella1,Terrenato Irene2ORCID,Giacomelli Luca34ORCID,Bifano Viviana1,Gravili Alessandra1,Faltyn Wioletta5,Ferraresi Virginia6,Favale Leonardo7,Petrongari Maria Grazia8,Salducca Nicola7,Vari Sabrina6,Falcicchio Chiara1,Rossi Barbara7,Biagini Roberto7,Pugliese Patrizia1

Affiliation:

1. Psychology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy

2. Biostatistic Unit – Scientific Direction, IRCCS Regina Elena National Cancer Institute, Rome, Italy

3. Polistudium SRL, Milan, Italy

4. Department of Surgical Sciences & Integrated Diagnostics, University of Genoa, Genoa, Italy

5. Sarcoma Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy

6. First Division of Medical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy

7. Orthopaedics Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy

8. Deptartment of Radiation Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy

Abstract

The aim of this study was to investigate symptoms, their variation over time and their relationship with quality of life (QoL)/psychological distress in sarcoma patients, as few data regarding QoL and psychological distress in this set of patients are currently available. A total of 188 sarcoma patients from an Italian referral center were involved. Symptoms and financial difficulties were evaluated with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire from the first treatment and over the follow-up period, up to 6 years. The authors found that patients with sarcoma experience several symptoms, especially fatigue and pain, which may dramatically worsen QoL and psychological distress. In conclusion, patients with sarcoma often experience fatigue, pain and financial difficulties, which negatively impacts QoL and psychological distress. To ameliorate overall QoL, proper control of symptoms is necessary.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

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