Oral health-related quality of life in oral cancer patients: systematic review and meta-analysis

Author:

Yuwanati Monal1ORCID,Gondivkar Shailesh2ORCID,Sarode Sachin C3ORCID,Gadbail Amol4ORCID,Desai Ami1ORCID,Mhaske Shubhangi1ORCID,Pathak Sandeep K5ORCID,N Khatib Mahalaqua6ORCID

Affiliation:

1. Department of Oral & Maxillofacial Pathology, People's College of Dental Sciences & Research Centre, People’s University, Bhopal, 462037, Madhya Pradesh, India

2. Department of Oral Medicine & Radiology, Government Dental College & Hospital, Nagpur, 440009, Maharashtra, India

3. Department of Oral Pathology & Microbiology, Dr DY Patil Dental College & Hospital, Dr DY Patil Vidyapeeth, Pune, 411018, Maharashtra, India

4. Department of Dentistry, Indira Gandhi Government Medical College & Hospital, Nagpur, 440018, Maharashtra, India

5. Central Library, Indian Institutes of Science Education & Research, Bhopal, 462006, Madhya Pradesh, India

6. Division of Evidence Synthesis, School of Epidemiology & Public Health, Datta Meghe Institute of Medical Sciences (DU), Wardha, 442004, Maharashtra, India

Abstract

Aim: The purpose of this meta-analysis was to evaluate the impact of oral health on quality of life in oral cancer patients (OCPs). Methods: PubMed, Scopus and Web of Science databases were searched for publications on oral health-related quality of life (OHRQoL) in OCP and the information was extracted according to the PRISMA guidelines. A random effect model was used to obtain the pooled standard mean differences of Oral Health Impact Profile (OHIP)-14 questionnaire responses in meta-analysis. Results: total of 12 research papers were analyzed and revealed poor OHRQoL in OCPs (standard mean difference: 2.53; 95% CI: 1.55–3.50; p < 0.00001) compared with healthy individuals due to the effects of oncotherapy. Moreover, OHRQoL deteriorated with combinations of different treatment modalities. Conclusion: Oral health and oncotherapy can affect the quality of life in OCPs.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

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