Clinico-radiological monitoring strategies in patients with metastatic breast cancer: a real-world study

Author:

Bonotto Marta1ORCID,Basile Debora12,Gerratana Lorenzo12,Bartoletti Michele12,Lisanti Camilla12,Pelizzari Giacomo12ORCID,Vitale Maria Grazia12,Fanotto Valentina12,Poletto Elena1,Minisini Alessandro Marco1,Russo Stefania1,Andreetta Claudia1,Mansutti Mauro1,Fasola Gianpiero1,Puglisi Fabio23ORCID

Affiliation:

1. Department of Oncology, University Academic Hospital, Udine, Italy

2. Department of Medicine, University of Udine, Udine, Italy

3. Department of Medical Oncology, Unit of Medical Oncology and Cancer Prevention, Centro di Riferimento Oncologico (CRO), IRCCS, National Cancer Institute, 33081 Aviano, Italy

Abstract

Aim: A monitoring strategy for metastatic breast cancer patients (M-MBC) has been little studied. Materials & methods: This retrospective study analyzed a consecutive cohort of 382 MBC patients to analyze different M-MBC strategies to identify factors influencing intensive M-MBC. Results: Elevated baseline serum tumor markers (STM) was the strongest factor associated with increased use of STM tests. Having more frequent oncology office visits was associated with more intensive chemotherapy/magnetic resonance imaging (MRI) using. Increased use of imaging tests was associated with participation to clinical trial. Single and elderly patients were less likely to have frequent testing. Having clinically measurable disease was less likely to have more intensive M-MBC. Conclusion: STM testing and scans were frequently ordered in M-MBC. In the present study, strategies are little influenced by clinico-pathological characteristics.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

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