Predictive lifestyle markers for efficacy of cancer immune checkpoint inhibitors: a commentary

Author:

Sillah Arthur12ORCID,Tykodi Scott S345,Hall Evan T345,Thompson John A345,Watson Nathaniel F6,Lee Sylvia M345,Bhatia Shailender345,Veatch Joshua345,Warner Jeannie4,Peters Ulrike12,Malen Rachel C2,Silverman Allison2,Phipps Amanda I12

Affiliation:

1. Department of Epidemiology, University of Washington School of Public Health, Seattle, WA 98195, USA

2. Epidemiology Program, Fred Hutchinson Research Cancer Research Center, Seattle, WA 98133, USA

3. Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98133, USA

4. Seattle Cancer Care Alliance, Seattle, WA 98133, USA

5. University of Washington School of Medicine, Division of Medical Oncology, Seattle, WA 98195, USA

6. University of Washington School of Medicine, Department of Neurology & University of Washington Sleep Medicine Center, Seattle, WA 98195, USA

Abstract

Lifestyle factors could plausibly modulate the host immune system, the tumor microenvironment and, hence, immune checkpoint inhibitor (ICI) response. As such, these factors should be considered in ICI studies.

Funder

Fred Hutchinson Cancer Research Center

National Institutes of Health Clinical Center

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

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