1. MRC Centre for Drug Safety Science, Department of Molecular & Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Sherrington Buildings, Ashton Street, Liverpool, L69 3GE, UK.
2. MRC Centre for Drug Safety Science, Department of Molecular & Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Sherrington Buildings, Ashton Street, Liverpool, L69 3GE, UK