Epstein-Barr and BK virus in cancerous and noncancerous prostate tissue-Reference-Cited by-同舟云学术

Epstein-Barr and BK virus in cancerous and noncancerous prostate tissue

Published:2020-01 Issue:1 Volume:15 Page:13-17
ISSN:1746-0794
Container-title:Future Virology
language:en
Short-container-title:Future Virology

Author:

Malekshahi Somayeh Shatizadeh¹,Yavarian Jila²,Salehi Robabeh²,Babaei Farhad³,Ahmadi Seyed Ali⁴,Ghavami Nastaran²,Naseri Maryam²,Hosseini Mostafa⁵,Mokhtari-Azad Talat²,Shafiei-Jandaghi Nazanin-Zahra²^ORCID

Affiliation:

1. Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

2. Virology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

3. Department of Microbiology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

4. Department of Pathology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

5. Department of Epidemiology & Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Aim: We conducted a case–control study to examine the presence of BK virus (BKV) and Epstein barr virus (EBV) genome in prostate specimens of benign prostatic hyperplasia (BPH) and prostate cancer (PCa) in Iran. Materials & methods: 64 paraffin-embedded PCa specimens were included as case subjects and 57 paraffin-embedded BPH specimens as control. DNA extraction was carried out by phenol–chloroform technique and PCR for detection of BKV and EBV. Results: 90 (73%) out of 121 specimens were collected by prostatectomy and 31 (27%) by transurethral resection of the prostate. BKV was not detected in any of the samples and one positive EBV was reported. Conclusion: These findings provide further evidence against a causative role of BKV and EBV in the development of PCa.

Publisher

Future Medicine Ltd

Subject

Virology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fvl-2019-0140

Reference31 articles.

1. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

2. Prostate Cancer in Iran: Trends in Incidence and Morphological and Epidemiological Characteristics

3. Inflammation in prostate carcinogenesis

4. Prospective investigation of risk factors for prostate cancer in the UK Biobank cohort study

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