Mortality-related risks in treatment-naive hospitalized AIDS patients with opportunistic infections in Southwest China

Abstract

Aim: We aimed to profile the characteristics and analyze the risk factors related to mortality in treatment-naive hospitalized AIDS patients with opportunistic infections (OIs) in Southwest China. Materials & methods: Two hundred and four treatment-naive patients diagnosed with AIDS-related OIs that were hospitalized in our hospital were enrolled. Their demographics, medical data and prognosis were described and analyzed. Result: Most patients were middle-aged married or cohabiting males. The infections in the respiratory system were the major OIs and leading cause of mortality. High CRP and IL-6 were identified as independent risk factors predicting mortality. Conclusion: Middle-aged treatment-naive males were the major victims of AIDS-related OIs. Respiratory infection should be monitored, and early intervention should be applied to improve prognosis if there is high CRP or IL-6 found.