Epithelial–mesenchymal transition in mouse mammary tumorigenesis-Reference-Cited by-同舟云学术

Epithelial–mesenchymal transition in mouse mammary tumorigenesis

Published:2009-10 Issue:8 Volume:5 Page:1113-1127
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Radaelli Enrico¹,Damonte Patrizia²,Cardiff Robert D³

Affiliation:

1. Department of Veterinary Pathology, Hygiene and Public Health, Section of Veterinary and Avian Pathology, Faculty of Veterinary Medicine, University of Milan, Via Celoria, 10 20133 Milano, Italy

2. Dipartimento di Medicina Sperimentale (DIMES), Università di Genova, Largo Rosanna Benzi 1o, 16132 Genova, Italy

3. Center for Comparative Medicine University of California, Davis, County Road 98 and Hutchison Drive, Davis, CA 95616, USA.

Abstract

Epithelial–mesenchymal transition tumorigenesis in the mouse has been described for over 100 years using various terms and with little comprehension of the underlying mechanisms. Recently, epithelial–mesenchymal transition tumors have been recognized in mammary glands of genetically engineered mice. This review provides a historical perspective and the current observations in the context of some of the key molecular biology. The biology of mouse mammary epithelial–mesenchymal transition tumorigenesis is discussed with comparisons to human breast cancer.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fon.09.93

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