Neurological and cognitive significance of probiotics: a holy grail deciding individual personality

Author:

Afzal Muhammad1ORCID,Mazhar Sayyeda Farwa1ORCID,Sana Sadia1,Naeem Muhammad1,Rasool Muhammad Hidayat2ORCID,Saqalein Muhammad2,Nisar Muhammad Atif2,Rasool Maria12,Bilal Muhammad3,Khan Abdul Arif4ORCID,Khurshid Mohsin2ORCID

Affiliation:

1. College of Allied Health Professionals, Directorate of Medical Sciences, Government College University Faisalabad, Pakistan

2. Department of Microbiology, Government College University Faisalabad, Pakistan

3. School of Life Science & Food Engineering, Huaiyin Institute of Technology, Huaian, Jiangsu, China

4. Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

Abstract

The role of the human microbiome in the brain and behavioral development is an area of increasing attention. Recent investigations have found that diverse mechanisms and signals including the immune, endocrine and neural associations are responsible for the communication between gut microbiota and the brain. The studies have suggested that alteration of intestinal microbiota using probiotic formulations may offer a significant role in the maturation and organization of the brain and can shape the brain and behavior as well as mood and cognition in human subjects. The understanding of the possible impact of gut microflora on neurological function is a promising phenomenon that can surely transform the neurosciences and may decipher the novel etiologies for neurodegenerative and psychiatric disorders.

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

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