Are mimotope vaccines a good alternative to monoclonal antibodies?

Abstract

Utilizing immunotherapy as a potential therapeutic approach to boost the body’s immune system for the fight against various diseases such as cancers, autoimmune diseases and also infections, is increasing day by day. Monoclonal antibodies, as effective therapeutic agents are used in cancer targeted therapies. However, these biologics have some disadvantages such as high costs and side effects. Therefore, emerging alternative immunotherapy strategies with high efficiency and low costs seems necessary. Mimotope vaccines, as epitope-mimicking structures, have shown to be effective therapeutic options, but are they really a good alternative to monoclonal antibodies, or are they just effective adjuvants?