Unlocking the potential of large language models in healthcare: navigating the opportunities and challenges

Author:

Tessler Idit12ORCID,Yamin Tzahi1ORCID,Peeri Hadar2ORCID,Alon Eran E1ORCID,Zimlichman Eyal2ORCID,Glicksberg Benjamin S3ORCID,Klang Eyal23ORCID

Affiliation:

1. Department of Otolaryngology - Head & Neck Surgery, Sheba Medical Center, affiliated to Tel Aviv University, Tel Aviv, Israel

2. The Sagol AI Hub, ARC Innovation Center, Sheba Medical Center, affiliated to Tel Aviv University, Israel

3. The Division of Data Driven & Digital Medicine (D3M), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA

Abstract

This paper explores the emerging role of large language models (LLMs) in healthcare, offering an analysis of their applications and limitations. Attention mechanisms and transformer architectures enable LLMs to perform tasks like extracting clinical information and assisting in diagnostics. We highlight research that demonstrates early application of LLMs in various domains and along the care pathway. With their promise, LLMs pose ethical and practical challenges, including data bias and the need for human oversight. This review serves as a guide for clinicians and researchers, outlining potential healthcare applications – ranging from document translation to clinical decision support – while cautioning about inherent limitations and ethical considerations. The aim of this work is to encourage the knowledgeable use of LLMs in healthcare and drive further study in this important emerging field.

Publisher

Informa UK Limited

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